Yes, in most cases you will be able but it depends on your engine type.
The internal switch in the MOB+ xHUB functions as a mechanical relay. This enables it to function as a traditional kill switch and hence if you have an engine already supporting a traditional lanyard your engine will also support the MOB+.
All outboard gasoline engines are fully supported by the MOB+.
For Quick Guide showing your specific engine brand, see here.
All gasoline engines are electronically controlled and can be switched using a mechanical switch. If your engine does not have an existing kill switch it will require you finding a suitable circuit to break to shut of the engine.
For newer diesel engines like Volvo Penta and Mercruiser, there is support for kill switch and connection can be made to the existing kill switch wires from the MOB+.
If your engine does not support a traditional lanyard with a mechanical shut-off switch then the MOB+ is not currently supported in your case.
Please see installation guide for general installation instructions and consult your local retailer or marina for more information.